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Edition of Prostaglandin E2 Receptors EP2 and EP4 by CRISPR/Cas9 Technology in Equine Adipose Mesenchymal Stem Cells

SIMPLE SUMMARY: Prostaglandin E2 plays a regulatory role in MSC self-renewal, and PGE2 receptor-mediated signalling is involved in cell proliferation and migration. The aim of this work was to establish a genetically modified equine cellular model in which receptor genes EP2 and EP4 were edited by t...

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Detalles Bibliográficos
Autores principales: Mançanares, Ana Carolina Furlanetto, Cabezas, Joel, Manríquez, José, de Oliveira, Vanessa Cristina, Wong Alvaro, Yat Sen, Rojas, Daniela, Navarrete Aguirre, Felipe, Rodriguez-Alvarez, Lleretny, Castro, Fidel Ovidio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341266/
https://www.ncbi.nlm.nih.gov/pubmed/32585798
http://dx.doi.org/10.3390/ani10061078