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Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine
BACKGROUND: We previously showed that the autophagy inhibitor chloroquine (CQ) increases inflammatory cleaved caspase-1 activity in myocytes, and that caspase-1/11 is protective in sterile liver injury. However, the role of caspase-1/11 in the recovery of muscle from ischemia caused by peripheral ar...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341481/ https://www.ncbi.nlm.nih.gov/pubmed/32641037 http://dx.doi.org/10.1186/s10020-020-00190-2 |