Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine

BACKGROUND: We previously showed that the autophagy inhibitor chloroquine (CQ) increases inflammatory cleaved caspase-1 activity in myocytes, and that caspase-1/11 is protective in sterile liver injury. However, the role of caspase-1/11 in the recovery of muscle from ischemia caused by peripheral ar...

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Detalles Bibliográficos
Autores principales: Sachdev, Ulka, Ferrari, Ricardo, Cui, Xiangdong, Pius, Abish, Sahu, Amrita, Reynolds, Michael, Liao, Hong, Sun, Ping, Shinde, Sunita, Ambrosio, Fabrisia, Shiva, Sruti, Loughran, Patricia, Scott, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341481/
https://www.ncbi.nlm.nih.gov/pubmed/32641037
http://dx.doi.org/10.1186/s10020-020-00190-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341481/
https://www.ncbi.nlm.nih.gov/pubmed/32641037
http://dx.doi.org/10.1186/s10020-020-00190-2

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