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Intravitreal Pharmacokinetic Study of the Antiangiogenic Glycoprotein Opticin

[Image: see text] Opticin is an endogenous vitreous glycoprotein that may have therapeutic potential as it has been shown that supranormal concentrations suppress preretinal neovascularization. Herein we investigated the pharmacokinetics of opticin following intravitreal injection in rabbits. To mea...

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Detalles Bibliográficos
Autores principales: del Amo, Eva M., Griffiths, John R., Klaska, Izabela P., Hoke, Justin, White, Anne, Aarons, Leon, Cooper, Garth J. S., Bainbridge, James W. B., Bishop, Paul N., Unwin, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341526/
https://www.ncbi.nlm.nih.gov/pubmed/32437164
http://dx.doi.org/10.1021/acs.molpharmaceut.0c00151