5-methoxytryptophan: an arsenal against vascular injury and inflammation

5-methoxytryptophan (5-MTP) is an endothelial factor with anti-inflammatory properties. It is synthesized from L-tryptophan via two enzymatic steps: tryptophan hydroxylase-1 (TPH-1) and hydroxyindole O-methyltransferase. Lipopolysaccharide (LPS) and pro-inflammatory cytokines suppress endothelial 5-...

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Detalles Bibliográficos
Autores principales: Wu, Kenneth K., Kuo, Cheng-Chin, Yet, Shaw-Fang, Lee, Chii-Ming, Liou, Jun-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341587/
https://www.ncbi.nlm.nih.gov/pubmed/32635910
http://dx.doi.org/10.1186/s12929-020-00671-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341587/
https://www.ncbi.nlm.nih.gov/pubmed/32635910
http://dx.doi.org/10.1186/s12929-020-00671-w

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