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Upregulation of fibronectin following loss of p53 function is a poor prognostic factor in ovarian carcinoma with a unique immunophenotype

BACKGROUND: We previously demonstrated that ovarian high grade serous carcinomas (OHGSeCa) and ovarian clear cell carcinomas (OCCCa) with an HNF-1β+/p53+/ARID1A+ immunophenotype were associated with the worst unfavorable prognosis. To clarify the molecular mechanisms underlying this finding, we focu...

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Detalles Bibliográficos
Autores principales: Yokoi, Ako, Matsumoto, Toshihide, Oguri, Yasuko, Hasegawa, Yoshinori, Tochimoto, Masataka, Nakagawa, Mayu, Saegusa, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341596/
https://www.ncbi.nlm.nih.gov/pubmed/32635925
http://dx.doi.org/10.1186/s12964-020-00580-3