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Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation with Cell-Cycle Progression in a Cyclin-Independent Manner

During mammalian meiotic prophase I, programmed DNA double-strand breaks are repaired by non-crossover or crossover events, the latter predominantly occurring via the class I crossover pathway and requiring the cyclin N-terminal domain-containing 1(CNTD1) protein. Using an epitope-tagged Cntd1 allel...

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Detalles Bibliográficos
Autores principales: Gray, Stephen, Santiago, Emerson R., Chappie, Joshua S., Cohen, Paula E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341696/
https://www.ncbi.nlm.nih.gov/pubmed/32640224
http://dx.doi.org/10.1016/j.celrep.2020.107858