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Cryo-EM structure of arabinosyltransferase EmbB from Mycobacterium smegmatis

Arabinosyltransferase B (EmbB) belongs to a family of membrane-bound glycosyltransferases that build the lipidated polysaccharides of the mycobacterial cell envelope, and are targets of anti-tuberculosis drug ethambutol. We present the 3.3 Å resolution single-particle cryo-electron microscopy struct...

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Detalles Bibliográficos
Autores principales: Tan, Yong Zi, Rodrigues, José, Keener, James E., Zheng, Ruixiang Blake, Brunton, Richard, Kloss, Brian, Giacometti, Sabrina I., Rosário, Ana L., Zhang, Lei, Niederweis, Michael, Clarke, Oliver B., Lowary, Todd L., Marty, Michael T., Archer, Margarida, Potter, Clinton S., Carragher, Bridget, Mancia, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341804/
https://www.ncbi.nlm.nih.gov/pubmed/32636380
http://dx.doi.org/10.1038/s41467-020-17202-8