Interferon-independent STING signaling promotes resistance to HSV-1 in vivo

The Stimulator of Interferon Genes (STING) pathway initiates potent immune responses upon recognition of DNA. To initiate signaling, serine 365 (S365) in the C-terminal tail (CTT) of STING is phosphorylated, leading to induction of type I interferons (IFNs). Additionally, evolutionary conserved resp...

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Detalles Bibliográficos
Autores principales: Yamashiro, Lívia H., Wilson, Stephen C., Morrison, Huntly M., Karalis, Vasiliki, Chung, Jing-Yi J., Chen, Katherine J., Bateup, Helen S., Szpara, Moriah L., Lee, Angus Y., Cox, Jeffery S., Vance, Russell E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341812/
https://www.ncbi.nlm.nih.gov/pubmed/32636381
http://dx.doi.org/10.1038/s41467-020-17156-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341812/
https://www.ncbi.nlm.nih.gov/pubmed/32636381
http://dx.doi.org/10.1038/s41467-020-17156-x

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