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A nanotrap improves survival in severe sepsis by attenuating hyperinflammation

Targeting single mediators has failed to reduce the mortality of sepsis. We developed a telodendrimer (TD) nanotrap (NT) to capture various biomolecules via multivalent, hybrid and synergistic interactions. Here, we report that the immobilization of TD-NTs in size-exclusive hydrogel resins simultane...

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Detalles Bibliográficos
Autores principales: Shi, Changying, Wang, Xiaojing, Wang, Lili, Meng, Qinghe, Guo, Dandan, Chen, Li, Dai, Matthew, Wang, Guirong, Cooney, Robert, Luo, Juntao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341815/
https://www.ncbi.nlm.nih.gov/pubmed/32636379
http://dx.doi.org/10.1038/s41467-020-17153-0