Hypo-Osmotic Loading Induces Expression of IL-6 in Nucleus Pulposus Cells of the Intervertebral Disc Independent of TRPV4 and TRPM7

Painful intervertebral disc (IVD) degeneration is an age-related process characterized by reduced tissue osmolarity, increased catabolism of the extracellular matrix, and elevated levels of pro-inflammatory molecules. With the aging population and constantly rising treatment costs, it is of utmost i...

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Detalles Bibliográficos
Autores principales: Sadowska, Aleksandra, Altinay, Birsen, Hitzl, Wolfgang, Ferguson, Stephen J., Wuertz-Kozak, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341822/
https://www.ncbi.nlm.nih.gov/pubmed/32714187
http://dx.doi.org/10.3389/fphar.2020.00952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341822/
https://www.ncbi.nlm.nih.gov/pubmed/32714187
http://dx.doi.org/10.3389/fphar.2020.00952

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