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Hypo-Osmotic Loading Induces Expression of IL-6 in Nucleus Pulposus Cells of the Intervertebral Disc Independent of TRPV4 and TRPM7
Painful intervertebral disc (IVD) degeneration is an age-related process characterized by reduced tissue osmolarity, increased catabolism of the extracellular matrix, and elevated levels of pro-inflammatory molecules. With the aging population and constantly rising treatment costs, it is of utmost i...
Autores principales: | Sadowska, Aleksandra, Altinay, Birsen, Hitzl, Wolfgang, Ferguson, Stephen J., Wuertz-Kozak, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341822/ https://www.ncbi.nlm.nih.gov/pubmed/32714187 http://dx.doi.org/10.3389/fphar.2020.00952 |
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