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Development and characterisation of NKp44‐based chimeric antigen receptors that confer T cells with NK cell‐like specificity
OBJECTIVES: One of the reasons as to why chimeric antigen receptors (CAR)‐T cell therapy for malignancies other than CD19‐ or BCMA‐positive tumors has yet to produce remarkable progress is the paucity of targetable antigens. NKp44 is only expressed by activated natural killer cells and detects a var...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341825/ https://www.ncbi.nlm.nih.gov/pubmed/32670576 http://dx.doi.org/10.1002/cti2.1147 |