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Development and characterisation of NKp44‐based chimeric antigen receptors that confer T cells with NK cell‐like specificity

OBJECTIVES: One of the reasons as to why chimeric antigen receptors (CAR)‐T cell therapy for malignancies other than CD19‐ or BCMA‐positive tumors has yet to produce remarkable progress is the paucity of targetable antigens. NKp44 is only expressed by activated natural killer cells and detects a var...

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Detalles Bibliográficos
Autores principales: Kasahara, Yasushi, Shin, Chansu, Kubo, Nobuhiro, Mihara, Keichiro, Iwabuchi, Haruko, Takachi, Takayuki, Imamura, Masaru, Saitoh, Akihiko, Imai, Chihaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341825/
https://www.ncbi.nlm.nih.gov/pubmed/32670576
http://dx.doi.org/10.1002/cti2.1147