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A time-dependent diffusion MRI signature of axon caliber variations and beading

MRI provides a unique non-invasive window into the brain, yet is limited to millimeter resolution, orders of magnitude coarser than cell dimensions. Here, we show that diffusion MRI is sensitive to the micrometer-scale variations in axon caliber or pathological beading, by identifying a signature po...

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Detalles Bibliográficos
Autores principales: Lee, Hong-Hsi, Papaioannou, Antonios, Kim, Sung-Lyoung, Novikov, Dmitry S., Fieremans, Els
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341838/
https://www.ncbi.nlm.nih.gov/pubmed/32636463
http://dx.doi.org/10.1038/s42003-020-1050-x