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Molecular profiling of stroma highlights stratifin as a novel biomarker of poor prognosis in pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer worldwide, as a result of a late diagnosis and limited therapeutic options. Tumour microenvironment (or stroma) plays a key role in cancer onset and progression and constitutes an intrinsic histological hallmark of PDAC. Thus we...

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Detalles Bibliográficos
Autores principales: Robin, Fabien, Angenard, Gaëlle, Cano, Luis, Courtin-Tanguy, Laetitia, Gaignard, Elodie, Khene, Zine-Eddine, Bergeat, Damien, Clément, Bruno, Boudjema, Karim, Coulouarn, Cédric, Sulpice, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341840/
https://www.ncbi.nlm.nih.gov/pubmed/32376891
http://dx.doi.org/10.1038/s41416-020-0863-1