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The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit

The hypothalamic suprachiasmatic nuclei (SCN) are the principal mammalian circadian timekeeper, co-ordinating organism-wide daily and seasonal rhythms. To achieve this, cell-autonomous circadian timing by the ~20,000 SCN cells is welded into a tight circuit-wide ensemble oscillation. This creates es...

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Detalles Bibliográficos
Autores principales: Patton, Andrew P., Edwards, Mathew D., Smyllie, Nicola J., Hamnett, Ryan, Chesham, Johanna E., Brancaccio, Marco, Maywood, Elizabeth S., Hastings, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341843/
https://www.ncbi.nlm.nih.gov/pubmed/32636383
http://dx.doi.org/10.1038/s41467-020-17110-x