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Toxicology of tramadol following chronic exposure based on metabolomics of the cerebrum in mice
Tramadol is an opioid used as an analgesic for treating moderate or severe pain. The long-term use of tramadol can induce several adverse effects. The toxicological mechanism of tramadol abuse is unclear. Metabolomics is a very useful method for investigating the toxicology of drug abuse. We investi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341866/ https://www.ncbi.nlm.nih.gov/pubmed/32636435 http://dx.doi.org/10.1038/s41598-020-67974-8 |