Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry

Meiotic divisions in oocytes are extremely asymmetric and require pre- and post-anaphase-onset phases of spindle migration. The latter induces membrane protrusion that is moulded around the spindle thereby reducing cytoplasmic loss. Here, we find that depleting the NAD biosynthetic enzyme, nicotinam...

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Detalles Bibliográficos
Autores principales: Wei, Zhe, Greaney, Jessica, Loh, Wei-Guo Nicholas, Homer, Hayden Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341875/
https://www.ncbi.nlm.nih.gov/pubmed/32636388
http://dx.doi.org/10.1038/s41467-020-17088-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341875/
https://www.ncbi.nlm.nih.gov/pubmed/32636388
http://dx.doi.org/10.1038/s41467-020-17088-6

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