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Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry
Meiotic divisions in oocytes are extremely asymmetric and require pre- and post-anaphase-onset phases of spindle migration. The latter induces membrane protrusion that is moulded around the spindle thereby reducing cytoplasmic loss. Here, we find that depleting the NAD biosynthetic enzyme, nicotinam...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341875/ https://www.ncbi.nlm.nih.gov/pubmed/32636388 http://dx.doi.org/10.1038/s41467-020-17088-6 |