R-loop induced G-quadruplex in non-template promotes transcription by successive R-loop formation

G-quadruplex (G4) is a noncanonical secondary structure of DNA or RNA which can enhance or repress gene expression, yet the underlying molecular mechanism remains uncertain. Here we show that when positioned downstream of transcription start site, the orientation of potential G4 forming sequence (PQ...

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Detalles Bibliográficos
Autores principales: Lee, Chun-Ying, McNerney, Christina, Ma, Kevin, Zhao, Walter, Wang, Ashley, Myong, Sua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341879/
https://www.ncbi.nlm.nih.gov/pubmed/32636376
http://dx.doi.org/10.1038/s41467-020-17176-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341879/
https://www.ncbi.nlm.nih.gov/pubmed/32636376
http://dx.doi.org/10.1038/s41467-020-17176-7

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