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DNA甲基化对白血病ABO基因表达的影响

OBJECTIVE: To investigate the impact of promoter CpG island methylation on ABO mRNA expression in leukemia. METHODS: 25 cases of leukemia and 20 cases of normal control were studied, and the leukemia cell lines K562、HL-60 and Jurkat were treated with different concentrations of decitabine. PCR-SSP w...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342105/
https://www.ncbi.nlm.nih.gov/pubmed/27719724
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2016.09.013