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PSMB5对多发性骨髓瘤细胞增殖和硼替佐米耐药的影响及其机制研究

OBJECTIVE: To investigate the effects of proteasome beta 5 subunit (PSMB5) on proliferation and bortezomib (BTZ) chemo-sensitivity of multiple myeloma (MM) and its related molecular mechanisms. METHODS: We used two MM cell lines, RPMI 8226 and BTZ drug-resistant cell line RPMI 8226/BTZ100 (hereinaft...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342182/
https://www.ncbi.nlm.nih.gov/pubmed/29365400
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2017.12.010