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PD-1抑制剂Nivolumab对CD19嵌合抗原受体T细胞体外增殖和杀伤活性的影响
OBJECTIVE: To Evaluation the effect of PD-1 inhibitor Nivolumab on the proliferation and cytotoxicity of anti-CD19 chimeric antigen receptor T cells (CD19-CAR-T) in vitro. METHODS: Five patients with high PD-1 expression in peripheral blood and five healthy volunteers were selected. These peripheral...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342209/ https://www.ncbi.nlm.nih.gov/pubmed/30122019 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2018.07.011 |