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PDK1在内皮细胞向造血细胞转换中的作用研究

OBJECTIVE: To explore the role of PDK1 in the transition of endothelial to hematopoietic cells and its effect on the generation and normal function of HSC. METHODS: PDK1 was deleted specifically in endothelial cells expressing VEC (Vascular Endothelial Cadherin). CFU-C was performed to detect the ef...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342253/
https://www.ncbi.nlm.nih.gov/pubmed/30369179
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2018.09.002