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Visualization of Epidermal Reservoir Formation from Topical Diclofenac Gels by Raman Spectroscopy

PURPOSE: This work investigated whether topical pain relief diclofenac gels can form a diclofenac reservoir in the epidermal and dermal layers of human skin. METHODS: Excised human skin samples were treated with three topical diclofenac gels ex vivo and examined using Raman microscopy of transversal...

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Detalles Bibliográficos
Autores principales: Zhang, Qihong, Flach, Carol R, Mendelsohn, Richard, Page, Leanne, Whitson, Susan, Boncheva Bettex, Mila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342390/
https://www.ncbi.nlm.nih.gov/pubmed/32753939
http://dx.doi.org/10.2147/JPR.S253069