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Response to Pyrotinib in a Chinese Patient with Bone-Metastatic Scrotal Paget’s Disease Harboring Triple Uncommon HER2 Mutation: A Case Report

BACKGROUND: Previous studies have suggested the efficacy of HER2 antibody (trastuzumab) in scrotal Paget’s disease with HER2 amplification or overexpression. However, no report about the effectiveness of HER2 inhibitor (pyrotinib) in those patients has been provided until now. CASE PRESENTATION: We...

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Detalles Bibliográficos
Autores principales: Guo, Jin-Ju, Jiao, Xiao-Dong, Wu, Ying, Qin, Bao-Dong, Liu, Ke, Zang, Yuan-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342492/
https://www.ncbi.nlm.nih.gov/pubmed/32753879
http://dx.doi.org/10.2147/OTT.S244814