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P210(T315I-BCR/ABL)转基因小鼠模型的建立与鉴定

OBJECTIVE: To construct the P210(T315I-BCR/ABL) transgenic mice model. METHODS: The transgenic vector in which the P210(T315I-BCR/ABL)gene and eGFP gene was derived by APN/CD13 promoter was constructed and microinjected into the single-cell fertilized eggs of C57 mice. Transgene integration was conf...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342520/
https://www.ncbi.nlm.nih.gov/pubmed/25854466
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2015.03.010