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酪氨酸激酶抑制剂治疗期间PH(−)细胞出现克隆性染色体异常对慢性髓性白血病患者预后的影响

OBJECTIVE: To investigate the characteristics and prognosis of clonal chromosomal abnormalities appearing in Philadelphia negative metaphases (CCA/Ph(−)) cells in chronic myeloid leukemia (CML) with tyrosine kinase inhibitor (TKI) therapy. METHODS: The clinical data of 30 cases with CCA/Ph(−) during...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342545/
https://www.ncbi.nlm.nih.gov/pubmed/30929388
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2019.03.009