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AMD3100阻断SDF-1 /CXCR4信号通路对白血病细胞与成骨龛黏附及耐药性的影响
OBJECTIVE: To study the blocking effect of CXCR4 inhibitor AMD3100 on the adhesion of leukemia cells to osteoblast niche, and the reversal of multidrug resistance in leukemia cells. METHODS: Mesenchymal stem cells (MSCs) from leukemia patients were planted on the bio-derived bone scaffolds and then...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342592/ https://www.ncbi.nlm.nih.gov/pubmed/26031530 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2015.05.013 |