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Sequential Whole Exome Sequencing Reveals Somatic Mutations Associated with Platinum Response in NSCLC

PURPOSE: Resistance is one of the main limitations of successful platinum treatment in non-small-cell lung cancer (NSCLC) patients. In this study, we aimed to identify somatic mutations associated with platinum response. PATIENTS AND METHODS: A total of 57 patients who received platinum-based chemot...

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Detalles Bibliográficos
Autores principales: Guo, Ao-Xiang, Xiao, Fan, Shao, Wei-Hua, Zhan, Yan, Zhang, Le, Xiong, Jing, Gao, Yang, Yin, Ji-Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342605/
https://www.ncbi.nlm.nih.gov/pubmed/32753889
http://dx.doi.org/10.2147/OTT.S254747