Cargando…

Sequential Whole Exome Sequencing Reveals Somatic Mutations Associated with Platinum Response in NSCLC

PURPOSE: Resistance is one of the main limitations of successful platinum treatment in non-small-cell lung cancer (NSCLC) patients. In this study, we aimed to identify somatic mutations associated with platinum response. PATIENTS AND METHODS: A total of 57 patients who received platinum-based chemot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Ao-Xiang, Xiao, Fan, Shao, Wei-Hua, Zhan, Yan, Zhang, Le, Xiong, Jing, Gao, Yang, Yin, Ji-Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342605/ https://www.ncbi.nlm.nih.gov/pubmed/32753889 http://dx.doi.org/10.2147/OTT.S254747

Ejemplares similares

Whole exome sequencing reveals somatic mutations in HRAS and KRAS which cause nevus sebaceus
por: Levinsohn, Jonathan L., et al.
Publicado: (2012)

Somatic mutations in renal cell carcinomas from Chinese patients revealed by whole exome sequencing
por: Wang, Jie, et al.
Publicado: (2018)

Whole exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas
por: Fishbein, Lauren, et al.
Publicado: (2015)

Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing
por: Helman, Elena, et al.
Publicado: (2014)

Whole-exome sequencing identifies somatic mutations and intratumor heterogeneity in inflammatory breast cancer
por: Luo, Rui, et al.
Publicado: (2021)

Comparison of somatic mutation calling methods in amplicon and whole exome sequence data
por: Xu, Huilei, et al.
Publicado: (2014)

Investigation of somatic mutation profiles and tumor evolution of primary oropharyngeal cancer and sequential lymph node metastases using multiregional whole‐exome sequencing
por: Sim, Nam Suk, et al.
Publicado: (2023)

Whole exome sequencing reveals novel somatic alterations in neuroblastoma patients with chemotherapy
por: Duan, Chao, et al.
Publicado: (2018)

Failure to Identify Somatic Mutations in Monozygotic Twins Discordant for Schizophrenia by Whole Exome Sequencing
por: Lyu, Nan, et al.
Publicado: (2016)

Whole-Exome Sequencing Identifies Novel Somatic Mutations in Chinese Breast Cancer Patients
por: Zhang, Yanfeng, et al.
Publicado: (2015)

Somatic Mutations from Whole Exome Sequencing Analysis of the Patients with Biliary Tract Cancer
por: Yoon, Kyong-Ah, et al.
Publicado: (2018)

Whole-exome sequencing identifies somatic mutations associated with lung cancer metastasis to the brain
por: Liu, Zhenghao, et al.
Publicado: (2021)

Accelerated somatic mutation calling for whole-genome and whole-exome sequencing data from heterogenous tumor samples
por: Ji, Shuangxi, et al.
Publicado: (2023)

Identification of somatic and germline mutations using whole exome sequencing of congenital acute lymphoblastic leukemia
por: Chang, Vivian Y, et al.
Publicado: (2013)

Identification of somatic mutations using whole-exome sequencing in Korean patients with acute myeloid leukemia
por: Heo, Seong Gu, et al.
Publicado: (2017)

Whole-Exome Sequencing Characterized the Landscape of Somatic Mutations and Pathways in Colorectal Cancer Liver Metastasis
por: Feng, Liuxing, et al.
Publicado: (2019)

Whole exome sequencing of multiple meningiomas with varying histopathological presentation in one patient revealed distinctive somatic mutation burden and independent clonal origins
por: Sheng, Han-Song, et al.
Publicado: (2019)

Data on somatic mutations obtained by whole exome sequencing of FFPE tissue samples from Russian patients with prostate cancer
por: Nikitina, A.S., et al.
Publicado: (2019)

Identification of somatic alterations in lipoma using whole exome sequencing
por: Kanojia, Deepika, et al.
Publicado: (2019)

Experimental Study of Somatic Variants of Osteosarcoma by Whole-Exome Sequencing
por: Hou, Jingyu, et al.
Publicado: (2020)

Whole-Exome Sequencing Reveals Mutational Signature of Hypertrophic Cardiomyopathy
por: Wang, Xi-Qin, et al.
Publicado: (2023)

AB165. Whole-exome sequencing characterizes the landscape of somatic mutations and copy number variations in testicular germ cell tumor
por: Wu, Song, et al.
Publicado: (2016)

Whole-exome sequencing to identify somatic mutations in peritoneal metastatic gastric adenocarcinoma: A preliminary study
por: Liu, Hao, et al.
Publicado: (2016)

Whole-Exome Sequencing Identifies Somatic Mutations Associated With Mortality in Metastatic Clear Cell Kidney Carcinoma
por: Mendoza-Alvarez, Alejandro, et al.
Publicado: (2019)

Germline and somatic mutations in the pathology of pineal cyst: A whole‐exome sequencing study of 93 individuals
por: Yan, Yuanqing, et al.
Publicado: (2021)

Somatic Mutation Profiling of Papillary Thyroid Carcinomas by Whole-exome Sequencing and Its Relationship with Clinical Characteristics
por: Qi, Tingyue, et al.
Publicado: (2021)

NSAID use and somatic exomic mutations in Barrett’s esophagus
por: Galipeau, Patricia C., et al.
Publicado: (2018)

AB201. Whole-exome sequencing characterizes the landscape of somatic mutations and copy number variations in testicular germ cell tumor
por: Wu, Song, et al.
Publicado: (2015)

Analysis of 7,815 cancer exomes reveals associations between mutational processes and somatic driver mutations
por: Poulos, Rebecca C., et al.
Publicado: (2018)

Whole-exome sequencing of epithelial ovarian carcinomas differing in resistance to platinum therapy
por: Hlaváč, Viktor, et al.
Publicado: (2022)

Whole-Exome Sequencing Revealed Mutations of MED12 and EFNB1 in Fetal Agenesis of the Corpus Callosum
por: Jiang, Ying, et al.
Publicado: (2019)

Whole-Exome Sequencing on Circulating Tumor Cells Explores Platinum-Drug Resistance Mutations in Advanced Non-small Cell Lung Cancer
por: Chang, Yuanyuan, et al.
Publicado: (2021)

Whole-exome sequencing reveals mutational profiles of anorectal and gynecological melanoma
por: Sun, Wei, et al.
Publicado: (2023)

Precise Identification of Recurrent Somatic Mutations in Oral Cancer Through Whole-Exome Sequencing Using Multiple Mutation Calling Pipelines
por: Lin, Li-Han, et al.
Publicado: (2021)

ExScalibur: A High-Performance Cloud-Enabled Suite for Whole Exome Germline and Somatic Mutation Identification
por: Bao, Riyue, et al.
Publicado: (2015)

CloneCNA: detecting subclonal somatic copy number alterations in heterogeneous tumor samples from whole-exome sequencing data
por: Yu, Zhenhua, et al.
Publicado: (2016)

MEDULLOBLASTOMA EXOME SEQUENCING UNCOVERS SUBTYPE-SPECIFIC SOMATIC MUTATIONS
por: Pugh, Trevor J., et al.
Publicado: (2012)

Exome-wide somatic mutation characterization of small bowel adenocarcinoma
por: Hänninen, Ulrika A., et al.
Publicado: (2018)

Detection of Somatic Mutations in Exome Sequencing of Tumor-only Samples
por: Hsu, Yu-Chin, et al.
Publicado: (2017)

Correction to: NSAID use and somatic exomic mutations in Barrett’s esophagus
por: Galipeau, Patricia C., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_83qsii9e9jpqcirf0po6bvqmhc