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共同抑制mTORC2和热休克蛋白90对多发性骨髓瘤细胞凋亡的影响
OBJECTIVE: To explore apoptosis of multiple myeloma (MM) cells and its mechanism by the combined inhibition of mTORC2 signaling pathway and heat shock protein 90. METHODS: The effects of Rapamycin, 17-AAG and the combination on proliferation of MM cell lines U266 and KM3 were assessed using MTT at d...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342707/ https://www.ncbi.nlm.nih.gov/pubmed/26462781 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2015.09.013 |