Cargando…
共同抑制mTORC2和热休克蛋白90对多发性骨髓瘤细胞凋亡的影响
OBJECTIVE: To explore apoptosis of multiple myeloma (MM) cells and its mechanism by the combined inhibition of mTORC2 signaling pathway and heat shock protein 90. METHODS: The effects of Rapamycin, 17-AAG and the combination on proliferation of MM cell lines U266 and KM3 were assessed using MTT at d...
Formato: | Online Artículo Texto |
---|---|
Lenguaje: | English |
Publicado: |
Editorial office of Chinese Journal of Hematology
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342707/ https://www.ncbi.nlm.nih.gov/pubmed/26462781 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2015.09.013 |
Ejemplares similares
-
热休克蛋白90抑制剂17-AAG对HUT-102细胞株JAK3/STAT5信号通路的影响
Publicado: (2017) -
miRNA-196b-5p和miRNA-99a-5p对多发性骨髓瘤细胞自噬及凋亡的影响
Publicado: (2018) -
苯乙肼对Molt-4细胞增殖、凋亡及组蛋白甲基化、乙酰化的影响
Publicado: (2016) -
色素上皮衍生因子及其多肽对非小细胞肺癌增殖、凋亡及迁移的影响
Publicado: (2021) -
载脂蛋白A1对多发性骨髓瘤预后的影响
Publicado: (2020)