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NPM1基因表达对急性髓系白血病细胞系的影响及其机制探讨

OBJECTIVE: To investigate the impact and mechanism of NPM1 gene expression on acute myeloid leukemia (AML) cell lines. METHODS: Human AML cell line U937 and HL-60 cells were transfected with NPM1 plasmid to establish stable clones, and the high NPM1 protein expression (NPM1(hi)) clones were screened...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342777/
https://www.ncbi.nlm.nih.gov/pubmed/29224316
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2017.11.008