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抑癌基因Hes1影响急性髓系白血病细胞增殖和凋亡的机制研究

OBJECTIVE: To elucidate the impact of Hes1 on the proliferation and apoptosis of acute myeloid leukemia (AML) cells. METHODS: The expression levels of Hes1 and p21 in AML patient samples and myeloid leukemia cell lines were analyzed by real-time PCR. Hes1 was up-regulated by retrovirus transfection...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343078/
https://www.ncbi.nlm.nih.gov/pubmed/26134013
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2015.06.008