Kinome capture sequencing of high-grade serous ovarian carcinoma reveals novel mutations in the JAK3 gene

High-grade serous ovarian carcinoma (HGSOC) remains the deadliest form of epithelial ovarian cancer and despite major efforts little improvement in overall survival has been achieved. Identification of recurring “driver” genetic lesions has the potential to enable design of novel therapies for cance...

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Detalles Bibliográficos
Autores principales: Mittempergher, Lorenza, Piskorz, Anna M., Bosma, Astrid J., Michaut, Magali, Wisman, G. Bea A., Kluin, Roelof J. C., Nieuwland, Marja, Brugman, Wim, van der Ven, Kevin J. W., Marass, Francesco, Morris, James, Rosenfeld, Nitzan, Jimenez-Linan, Mercedes, de Jong, Steven, van der Zee, Ate G. J., Brenton, James D., Bernards, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343160/
https://www.ncbi.nlm.nih.gov/pubmed/32639993
http://dx.doi.org/10.1371/journal.pone.0235766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343160/
https://www.ncbi.nlm.nih.gov/pubmed/32639993
http://dx.doi.org/10.1371/journal.pone.0235766

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