Mechanobiological model for simulation of injured cartilage degradation via pro-inflammatory cytokines and mechanical stimulus

Post-traumatic osteoarthritis (PTOA) is associated with cartilage degradation, ultimately leading to disability and decrease of quality of life. Two key mechanisms have been suggested to occur in PTOA: tissue inflammation and abnormal biomechanical loading. Both mechanisms have been suggested to res...

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Detalles Bibliográficos
Autores principales: Eskelinen, Atte S. A., Tanska, Petri, Florea, Cristina, Orozco, Gustavo A., Julkunen, Petro, Grodzinsky, Alan J., Korhonen, Rami K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343184/
https://www.ncbi.nlm.nih.gov/pubmed/32584809
http://dx.doi.org/10.1371/journal.pcbi.1007998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343184/
https://www.ncbi.nlm.nih.gov/pubmed/32584809
http://dx.doi.org/10.1371/journal.pcbi.1007998

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