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Epigenome-based splicing prediction using a recurrent neural network

Alternative RNA splicing provides an important means to expand metazoan transcriptome diversity. Contrary to what was accepted previously, splicing is now thought to predominantly take place during transcription. Motivated by emerging data showing the physical proximity of the spliceosome to Pol II,...

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Detalles Bibliográficos
Autores principales: Lee, Donghoon, Zhang, Jing, Liu, Jason, Gerstein, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343189/
https://www.ncbi.nlm.nih.gov/pubmed/32584815
http://dx.doi.org/10.1371/journal.pcbi.1008006