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Ankyrin Is An Intracellular Tether for TMC Mechanotransduction Channels

Mechanotransduction channels have been proposed as force sensors in various physiological processes, such as hearing and touch. In particular, TMC1 has been shown to constitute the pore of hair cell mechanotransduction channels, but little is known about how force is sensed by TMC channels. Here, we...

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Detalles Bibliográficos
Autores principales: Tang, Yi-Quan, Lee, Sol Ah, Rahman, Mizanur, Vanapalli, Siva A., Lu, Hang, Schafer, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343241/
https://www.ncbi.nlm.nih.gov/pubmed/32325031
http://dx.doi.org/10.1016/j.neuron.2020.03.026