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Sirt1 gene confers Adriamycin resistance in DLBCL via activating the PCG-1α mitochondrial metabolic pathway

Sirt1 is closely related to cells aging, and Sirt1 also plays an important role in diffuse large B-cell lymphoma (DLBCL). However, its mechanism remains unclear. Therefore, we investigated the mechanism of Sirt1 mediated drug-resistance in DLBCL, while the recombinant lentivirus was used to regulate...

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Detalles Bibliográficos
Autores principales: Zhou, Zhen, Ma, Dan, Li, Peifan, Wang, Ping, Liu, Ping, Wei, Danna, Wang, Jun, Qin, Zhong, Fang, Qin, Wang, Jishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343448/
https://www.ncbi.nlm.nih.gov/pubmed/32570218
http://dx.doi.org/10.18632/aging.103174