Endothelin-1 induces cellular senescence and fibrosis in cultured myoblasts. A potential mechanism of aging-related sarcopenia

Endothelial dysfunction, with increased endothelin-1 (ET-1) synthesis, and sarcopenia, characterized by the loss of muscular mass and strength, are two aging–related conditions. However, a relationship between them has not been already established. The aim of this study was to determine whether ET-1...

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Detalles Bibliográficos
Autores principales: Alcalde-Estévez, Elena, Asenjo-Bueno, Ana, Sosa, Patricia, Olmos, Gemma, Plaza, Patricia, Caballero-Mora, María Ángeles, Rodríguez-Puyol, Diego, Ruíz-Torres, María Piedad, López-Ongil, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343454/
https://www.ncbi.nlm.nih.gov/pubmed/32572011
http://dx.doi.org/10.18632/aging.103450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343454/
https://www.ncbi.nlm.nih.gov/pubmed/32572011
http://dx.doi.org/10.18632/aging.103450

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