Cargando…

Agonism of GPR120 prevented IL-1β-induced reduction of extracellular matrix through SOX-9

Osteoarthritis (OA) is a whole-joint disease with extremely high prevalence. In all treatment approaches of OA, blocking the degradation of the cartilage extracellular matrix is an important treatment. In OA, overexpression of derivative enzymes leads to excessive catabolism and reduced synthesis of...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Zhixian, Ke, Tie, Zhang, Yongfa, Fu, Chaofeng, He, Wubing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343462/
https://www.ncbi.nlm.nih.gov/pubmed/32580167
http://dx.doi.org/10.18632/aging.103375