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Long noncoding RNA KCNQ1OT1 promotes colorectal carcinogenesis by enhancing aerobic glycolysis via hexokinase-2

In this study, we investigated the mechanistic role and prognostic significance of the long coding RNA (lncRNA) KCNQ1OT1 in colorectal cancer (CRC). KCNQ1OT1 levels were significantly higher in CRC tissues than adjacent normal colorectal tissues (n=79). High KCNQ1OT1 expression correlated with poore...

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Detalles Bibliográficos
Autores principales: Chen, Cheng, Wei, Meng, Wang, Chao, Sun, Danping, Liu, Peng, Zhong, Xin, Yu, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343465/
https://www.ncbi.nlm.nih.gov/pubmed/32564010
http://dx.doi.org/10.18632/aging.103334