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Transient metabolic improvement in obese mice treated with navitoclax or dasatinib/quercetin

Senescent cells accumulate with obesity in the white adipose tissue of mice and humans. These senescent cells enhance the pro-inflammatory environment that, with time, contributes to the onset of glucose intolerance and type 2 diabetes. Glucose intolerance in mouse models of obesity has been success...

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Detalles Bibliográficos
Autores principales: Sierra-Ramirez, Arantzazu, López-Aceituno, José Luis, Costa-Machado, Luis Filipe, Plaza, Adrián, Barradas, Marta, Fernandez-Marcos, Pablo Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343475/
https://www.ncbi.nlm.nih.gov/pubmed/32584785
http://dx.doi.org/10.18632/aging.103607