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Androgen receptor affects the response to immune checkpoint therapy by suppressing PD-L1 in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a heterogeneous malignancy with gender-related differences in onset and course. Androgen receptor (AR), a male hormone receptor, is critical in the initiation and progression of HCC. The role of AR in HCC has been mechanistically characterized and anti-AR therapies...

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Detalles Bibliográficos
Autores principales: Jiang, Guangyi, Shi, Liang, Zheng, Xueyong, Zhang, Xinjie, Wu, Ke, Liu, Boqiang, Yan, Peijian, Liang, Xiao, Yu, Tunan, Wang, Yifan, Cai, Xiujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343489/
https://www.ncbi.nlm.nih.gov/pubmed/32579541
http://dx.doi.org/10.18632/aging.103231