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Hybrid Magnetic Nanovectors Promote Selective Glioblastoma Cell Death through a Combined Effect of Lysosomal Membrane Permeabilization and Chemotherapy

[Image: see text] Glioblastoma multiforme is the most aggressive brain tumor, due to its high invasiveness and genetic heterogeneity. Moreover, the blood–brain barrier prevents many drugs from reaching a therapeutic concentration at the tumor site, and most of the chemotherapeutics lack in specifici...

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Detalles Bibliográficos
Autores principales: Pucci, Carlotta, De Pasquale, Daniele, Marino, Attilio, Martinelli, Chiara, Lauciello, Simone, Ciofani, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343532/
https://www.ncbi.nlm.nih.gov/pubmed/32459082
http://dx.doi.org/10.1021/acsami.0c05556