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Site-Dependent Cysteine Lipidation Potentiates the Activation of Proapoptotic BAX

BCL-2 family proteins converge at the mitochondrial outer membrane to regulate apoptosis and maintain the critical balance between cellular life and death. This physiologic process is essential to organism homeostasis and relies on protein-protein and protein-lipid interactions among BCL-2 family pr...

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Detalles Bibliográficos
Autores principales: Cohen, Daniel T., Wales, Thomas E., McHenry, Matthew W., Engen, John R., Walensky, Loren D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343539/
https://www.ncbi.nlm.nih.gov/pubmed/32160532
http://dx.doi.org/10.1016/j.celrep.2020.02.057