Natural soluble human leukocyte antigen class I in donor serum neutralizes donor-specific HLA alloantibodies in recipient serum

BACKGROUND: Human leukocyte antigen (HLA) molecules are cell-bound but can be identified in a soluble form. These soluble HLA (sHLA) molecules have an immunomodulatory function. We investigated whether natural sHLA in donor serum can neutralize donor-specific HLA alloantibodies (DSAs) in recipient s...

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Detalles Bibliográficos
Autores principales: Won, Dong Il, Lee, Nan Young, Lim, Jeong-Hoon, Han, Young Seok, Kim, Chan-Duck, Huh, Seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343548/
https://www.ncbi.nlm.nih.gov/pubmed/32429622
http://dx.doi.org/10.5045/br.2020.2020031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343548/
https://www.ncbi.nlm.nih.gov/pubmed/32429622
http://dx.doi.org/10.5045/br.2020.2020031

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