Lymph node metastases develop through a wider evolutionary bottleneck than distant metastases

Genetic diversity among metastases is poorly understood but contains important information about disease evolution at secondary sites. Here we investigate inter- and intra-lesion heterogeneity for two types of metastases that associate with different clinical outcomes: lymph node and distant organ m...

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Detalles Bibliográficos
Autores principales: Reiter, Johannes G., Hung, Wei-Ting, Lee, I-Hsiu, Nagpal, Shriya, Giunta, Peter, Degner, Sebastian, Liu, Gang, Wassenaar, Emma C.E., Jeck, William R., Taylor, Martin S., Farahani, Alexander A., Marble, Hetal D., Knott, Simon, Kranenburg, Onno, Lennerz, Jochen K., Naxerova, Kamila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343611/
https://www.ncbi.nlm.nih.gov/pubmed/32451459
http://dx.doi.org/10.1038/s41588-020-0633-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343611/
https://www.ncbi.nlm.nih.gov/pubmed/32451459
http://dx.doi.org/10.1038/s41588-020-0633-2

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