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Lymph node metastases develop through a wider evolutionary bottleneck than distant metastases
Genetic diversity among metastases is poorly understood but contains important information about disease evolution at secondary sites. Here we investigate inter- and intra-lesion heterogeneity for two types of metastases that associate with different clinical outcomes: lymph node and distant organ m...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343611/ https://www.ncbi.nlm.nih.gov/pubmed/32451459 http://dx.doi.org/10.1038/s41588-020-0633-2 |